Cenforce 200 is one of the safest male impotence pills on the market. Cenforce 200 works by increasing blood flow to the penile area, allowing men to get and maintain an erection for hours. This medication belongs to a class of medications known as PDE5 inhibitors, and it was accidentally discovered to treat ED in men. It is taken either on an empty stomach or with food, about an hour before sexual activity. It typically takes 30 minutes to an hour to take effect.